| Desmodium sericocarpum Hemsl., 1880 |
| Desmodium sericophyllum Schltdl., 1838 |
| Desmodium sericophyllum var. strobilaceum (Schltdl.) N. Zamora, 2000 |
| Desmodium serotinum (Willd.) DC., 1825 |
| Desmodium sessilifolium Torr. & A. Gray, 1840 |
| Desmodium skinneri Benth. ex Hemsl., 1880 |
| Desmodium skinneri var. curtum (M.E. Jones) B.G. Schub. & McVaugh, 1987 |
| Desmodium skinneri var. flavovirens B.G. Schub. & McVaugh, 1987 |
| Desmodium skinneri var. mortonii B.G. Schub. & McVaugh, 1987 |
| Desmodium sonorae A. Gray, 1853 |
| Desmodium spicatum Rehder, 1922 |
| Desmodium spirale (Sw.) DC., 1825 |
| Desmodium spirale var. annuum (A. Gray) B.L. Rob. & Greenm., 1894 |
| Desmodium spirale var. bigelovii (A. Gray) B.L. Rob. & Greenm., 1894 |
| Desmodium spirale var. transversum B.L. Rob. & Greenm., 1894 |
| Desmodium strobilaceum Schltdl., 1838 |
| Desmodium subrosum G.L. Nesom, 1994 |
| Desmodium subsessile B.L. Rob. & Seaton, 1893 |
| Desmodium subsessile Schltdl., 1838 |
| Desmodium subspicatum S. Watson, 1891 |