| Desmodium lilloanum (Schindl.) Burkart, 1939 |
| Desmodium lindheimeri Vail, 1891 |
| Desmodium lineatum (Michx.) DC., 1825 |
| Desmodium lupulinum Schltdl., 1838 |
| Desmodium luteocanescens M.E. Jones, 1929 |
| Desmodium luteolum Standl., 1938 |
| Desmodium macrodesmum (S.F. Blake) Standl. & Steyerm., 1946 |
| Desmodium macropodium Hemsl., 1880 |
| Desmodium macrostachyum Hemsl., 1880 |
| Desmodium madrense Hemsl., 1880 |
| Desmodium maxonii (Standl.) Standl., 1936 |
| Desmodium metallicum (Rose & Standl.) Standl., 1936 |
| Desmodium mexiae B.G. Schub., 1941 |
| Desmodium mexicanum S. Watson, 1888 |
| Desmodium michelianum (Schindl.) B.G. Schub. & McVaugh, 1987 |
| Desmodium michoacanum B.G. Schub. & McVaugh, 1987 |
| Desmodium molle (Vahl) DC., 1768 |
| Desmodium molliculum (Kunth) DC., 1825 |
| Desmodium monticola Brandegee, 1924 |
| Desmodium neomexicanum A. Gray, 1852 |