| Desmodium purpureum (Mill.) Fawc. & Rendle, 1920 |
| Desmodium purpusianum (Schindl.) B.G. Schub., 1941 |
| Desmodium purpusii Brandegee, 1914 |
| Desmodium quercetorum Standl., 1937 |
| Desmodium racemiferum DC., 1825 |
| Desmodium raymundoramirezii L. Torres & A. Delgado, 2015 |
| Desmodium retinens Schltdl., 1838 |
| Desmodium rhabdocladum Franch., 1889 |
| Desmodium robinsonii (Standl.) Standl., 1929 |
| Desmodium rosei B.G. Schub., 1940 |
| Desmodium rubricaule (Rose & Painter) Riley, 1923 |
| Desmodium saxatile (Morton) B.G. Schub. & McVaugh, 1987 |
| Desmodium scalare B.G. Schub. & McVaugh, 1987 |
| Desmodium schindleri B.G. Schub., 1941 |
| Desmodium schusteri (Schindl.) Standl., 1936 |
| Desmodium scopulorum S. Watson, 1889 |
| Desmodium scorpiurus (Sw.) Poir., 1819 |
| Desmodium scutatum Hemsl., 1880 |
| Desmodium seatonii Greenm., 1903 |
| Desmodium sericeum (Schindl.) Standl., 1937 |