| Sceloporus smithi Hartweg & Oliver, 1937 |
| Sceloporus spinosus Wiegmann, 1828 |
| Sceloporus spinosus subsp. apicalis P. W. Smith & H. M. Smith, 1951 |
| Sceloporus spinosus subsp. caeruleopunctatus Smith, 1938 |
| Sceloporus spinosus subsp. floridanus Stejneger, 1893 |
| Sceloporus spinosus subsp. horridus Wiegmann, 1834 |
| Sceloporus spinosus subsp. magister Hallowell, 1854 |
| Sceloporus spinosus subsp. spinosus Wiegmann, 1828 |
| Sceloporus squamosus Bocourt, 1874 |
| Sceloporus squamosus subsp. smaragdinus Bocourt, 1873 |
| Sceloporus stejnegeri Smith, 1942 |
| Sceloporus subniger Poglayen & Smith, 1958 |
| Sceloporus subpictus Lynch & Smith, 1965 |
| Sceloporus sugillatus Smith, 1942 |
| Sceloporus taeniocnemis Cope, 1885 |
| Sceloporus taeniocnemis subsp. hartwegi Stuart, 1971 |
| Sceloporus taeniocnemis subsp. taeniocnemis Cope, 1885 |
| Sceloporus tanneri Smith & Larsen, 1975 |
| Sceloporus teapensis Günther, 1890 |
| Sceloporus torquatus Wiegmann, 1828 |