| Sceloporus rufidorsum Yarrow, 1882 |
| Sceloporus salvini Günther, 1890 |
| Sceloporus samcolemani Smith & Hall, 1974 |
| Sceloporus scalaris Wiegmann, 1828 |
| Sceloporus scalaris subsp. brownorum Smith, Watkins-Colwell, Lemos-Espinal & Chiszar, 1997 |
| Sceloporus scalaris subsp. samcolemani Smith & Hall, 1974 |
| Sceloporus scalaris subsp. scalaris Wiegmann, 1828 |
| Sceloporus scalaris subsp. slevini Smith, 1937 |
| Sceloporus scitulus Smith, 1942 |
| Sceloporus serrifer Cope, 1866 |
| Sceloporus serrifer subsp. cariniceps Martin, 1952 |
| Sceloporus serrifer subsp. cyanogenys Cope, 1885 |
| Sceloporus serrifer subsp. plioporus Smith, 1939 |
| Sceloporus serrifer subsp. prezygus Smith, 1942 |
| Sceloporus serrifer subsp. serrifer Cope, 1866 |
| Sceloporus shannonorum Langebartel, 1959 |
| Sceloporus siniferus Cope, 1870 |
| Sceloporus siniferus subsp. siniferus Cope, 1870 |
| Sceloporus slevini Smith, 1937 |
| Sceloporus smaragdinus Bocourt, 1873 |