| Ypophaemyia Townsend, 1916 |
| Zaira Robineau-Desvoidy, 1830 |
| Zaira adscripta (Wulp, 1890) |
| Zaira medeola (Reinhard, 1961) |
| Zaira nubecula (Wulp, 1890) |
| Zaira robusta (Wulp, 1890) |
| Zaira sublucens (Wulp, 1890) |
| Zelia Robineau-Desvoidy, 1830 |
| Zelia gracilis (Wiedemann, 1830) |
| Zelia semirufa (Wulp, 1891) |
| Zelia spectabilis (Wulp, 1891) |
| Zelia tricolor (Coquillett, 1899) |
| Zelia verterbrata (Say, 1829) |
| Zeliini Townsend, 1919 |
| Zenillia Robineau-Desvoidy, 1830 |
| Zenillia angustata (Wulp, 1890) |
| Zizyphomyia Townsend, 1916 |
| Zizyphomyia crescentis (Reinhard, 1944) |
| Zygofrontina Townsend, 1915 |
| Zygosturmia Townsend, 1911 |