| Solanum splendens (Dunal) Bohs, 2015 |
| Solanum squamulosum M. Martens & Galeotti, 1845 |
| Solanum stellatum Ruiz & Pav., 1799 |
| Solanum stephanocalyx Brandegee, 1917 |
| Solanum sylvicola Brandegee, 1917 |
| Solanum symphysicaulis Pav. ex Dunal, 1852 |
| Solanum synantherum Sendtn., 1846 |
| Solanum tampicense Dunal, 1852 |
| Solanum tarapotense Van Heurck & Müll. Arg., 1870 |
| Solanum tenellum Bitter, 1912 |
| Solanum tenuilobatum Parish, 1901 |
| Solanum tequilense A. Gray, 1887 |
| Solanum texense Engelm. & A. Gray, 1845 |
| Solanum tlacotalpense Sessé & Moc., 1892 |
| Solanum tlaxcalense Hawkes, 1944 |
| Solanum tricolor Sessé & Moc. ex Dunal, 1814 |
| Solanum triste Jacq., 1760 |
| Solanum umbellatum Mill., 1768 |
| Solanum unguis-cati Standl., 1929 |
| Solanum uniflorum Sessé ex Lag., 1816 |