| Conepatus tropicalis subsp. yucatanicus Goldman, 1943 |
| Mephitidae Bonaparte, 1845 |
| Mephitis É. Geoffroy St. -Hilaire & G. Cuvier, 1795 |
| Mephitis concolor J. E. Gray, 1865 |
| Mephitis edulis Coues, 1877 |
| Mephitis estor Merriam, 1890 |
| Mephitis interrupta Rafinesque, 1820 |
| Mephitis leuconata Lichtenstein, 1832 |
| Mephitis longicaudata Tomes, 1862 |
| Mephitis macroura Lichtenstein, 1832 |
| Mephitis macroura subsp. eximius Hall & Dalquest, 1950 |
| Mephitis macroura subsp. macroura Lichtenstein, 1832 |
| Mephitis macroura subsp. milleri Mearns, 1897 |
| Mephitis macroura subsp. vittata J. A. Allen, 1901 |
| Mephitis mephitica Coues, 1887 |
| Mephitis mephitis (Schreber, 1776) |
| Mephitis mephitis subsp. estor Merriam, 1890 |
| Mephitis mephitis subsp. holzneri Mearns, 1897 |
| Mephitis mephitis subsp. varians J. E. Gray, 1837 |
| Mephitis milleri Mearns, 1897 |