| Hyptis intermedia Epling, 1940 |
| Hyptis involucrata Benth., 1833 |
| Hyptis iodantha Epling, 1939 |
| Hyptis jurgensenii Briq., 1898 |
| Hyptis langlassei Fernald, 1910 |
| Hyptis laniflora Benth., 1844 |
| Hyptis lantanifolia Poit., 1806 |
| Hyptis lilacina Cham. & Schltdl., 1830 |
| Hyptis lilacina var. epimallota Briq., 1898 |
| Hyptis lophantha Mart. ex Benth., 1833 |
| Hyptis lutescens Pohl ex Benth., 1833 |
| Hyptis macrocephala M. Martens & Galeotti, 1844 |
| Hyptis macrochila Mart. ex Steud., 1840 |
| Hyptis macvaughii J.G. González & Art. Castro, 2014 |
| Hyptis madrensis Fernald, 1900 |
| Hyptis mariannarum Briq., 1897 |
| Hyptis mixta Epling, 1944 |
| Hyptis mociniana Benth., 1833 |
| Hyptis mutabilis (Rich.) Briq., 1896 |
| Hyptis mutabilis var. polystachya (Kunth) Briq., 1897 |