| Didelphis lanata Olfers, 1818 |
| Didelphis marsupialis Linnaeus, 1758 |
| Didelphis marsupialis subsp. battyi Thomas, 1902 |
| Didelphis marsupialis subsp. caucae J. A. Allen, 1900 |
| Didelphis marsupialis subsp. colombica J. A. Allen, 1902 |
| Didelphis marsupialis subsp. etensis J. A. Allen, 1902 |
| Didelphis marsupialis subsp. mesamericana Dalquest, 1953 |
| Didelphis marsupialis subsp. particeps Goldman, 1917 |
| Didelphis marsupialis subsp. tabascensis J. A. Allen, 1901 |
| Didelphis mesamericana Miller, 1924 |
| Didelphis mesamericana subsp. mesamericana Miller, 1924 |
| Didelphis murina Sumichrast, 1881 |
| Didelphis opossum Linnaeus, 1758 |
| Didelphis pruinosa Wagner, 1843 |
| Didelphis richmondi J. A. Allen, 1901 |
| Didelphis virginiana Kerr, 1792 |
| Didelphis virginiana subsp. californica Bennett, 1833 |
| Didelphis virginiana subsp. virginiana Kerr, 1792 |
| Didelphis virginiana subsp. yucatanensis J. A. Allen, 1901 |
| Didelphis yucatanensis J. A. Allen, 1901 |