| Agave (Agave) datylio var. vexans (Trel.) I.M. Johnst., 1924 |
| Agave (Agave) densispina F. Cels, 1865 |
| Agave (Agave) dentiens Trel., 1911 |
| Agave (Agave) deserti Engelm., 1875 |
| Agave (Agave) deserti subsp. deserti Engelm., 1875 |
| Agave (Agave) deserti subsp. pringlei (Engelm. ex Baker) Gentry, 1978 |
| Agave (Agave) deserti subsp. simplex Gentry, 1978 |
| Agave (Agave) deserti var. pringlei (Baker) W.C. Hodgs. & Reveal, 2001 |
| Agave (Agave) desmetiana Jacobi, 1866 |
| Agave (Agave) desmetiana Baker, 1877 |
| Agave (Agave) deweyana Trel., 1909 |
| Agave (Agave) disjuncta Trel., 1911 |
| Agave (Agave) donnell-smithii (Baker) Mez, 1915 |
| Agave (Agave) durangensis Gentry, 1982 |
| Agave (Agave) eichlamii A. Berger, 1915 |
| Agave (Agave) elegans hort. ex Salm-Dyck, 1859 |
| Agave (Agave) elongata Jacobi, 1864 |
| Agave (Agave) endlichiana Trel., 1909 |
| Agave (Agave) expansa Jacobi, 1868 |
| Agave (Agave) exselsa Baker, 1877 |