| Hesperastragalus A. Heller, 1905 |
| Hesperastragalus brazoensis (Buckley) Rydb., 1926 |
| Hesperastragalus compactus A. Heller, 1906 |
| Hesperastragalus didymocarpus (Hook. & Arn.) A. Heller, 1905 |
| Hesperastragalus diphacus (S. Watson) Rydb., 1926 |
| Hesperastragalus dispermus (A. Gray) A. Heller, 1906 |
| Hesperastragalus elmeri (Greene) Rydb., 1926 |
| Hesperastragalus gambellianus (E. Sheld.) A. Heller, 1905 |
| Hesperastragalus obispensis Rydb., 1926 |
| Hesperastragalus oxyrhynchus (Hemsl.) Rydb., 1926 |
| Hesperastragalus peonis (M.E. Jones) Rydb., 1929 |
| Hesperothamnus Brandegee, 1919 |
| Hesperothamnus brachycalyx Rydb., 1924 |
| Hesperothamnus ehrenbergii (Harms) Harms, 1923 |
| Hesperothamnus grandis Standl., 1922 |
| Hesperothamnus heptaphyllus M. Sousa ex Cruz Durán & G. Andrade, 2024 |
| Hesperothamnus littoralis (Brandegee) Brandegee, 1919 |
| Hesperothamnus michoacanicus M. Sousa ex Cruz Durán & G. Andrade, 2024 |
| Hesperothamnus pentaphyllus (Harms) Harms, 1923 |
| Hesperothamnus purpusii (Harms) Harms, 1923 |